The Eiger Trail is nice (Swiss alps). Its a bit of a linear route though. I started it at Grindelwald and ended at the Eigergletscher train station. Most people would probably get the "rip off" train back. But I ran a less interesting trail / road back.

I agree with the Chamonix run, I always get the free bus to Col Du Montets. You can extend this towards the end by going to Aiguilette des Houches, taking Le Brevent on the way, then back to Chamonix.

Going up Mont buet from the train station is a nice run with a bit of possible variation. It is also a 10,000 + feet peak.