Page 2 of 9 FirstFirst 1234 ... LastLast
Results 11 to 20 of 85

Thread: Glucosamine

  1. #11
    Member
    Join Date
    Jun 2008
    Location
    Up North
    Posts
    35

    Re: Glucosamine

    Quote Originally Posted by christopher leigh View Post
    Twister for Glucosamine to work it would have to pass from the gut into the blood unchanged. Then the liver would have to prepare it for use in the joints. From the liver it would be carried via the blood to the exact place it's needed, and be incorporated into the joint.

    Very unlikely! The reason being that Glucosamine is an Amino sugar. Once in the stomach it will be broken down into Amino acids and sugar, just like food. If that wasn't the case it would be found in the blood, and as far as I understand it, it isn't.

    Insulin is a polypeptide and has to be injected. If you swallowed it the body would break it down into it's component Amino acids, making it useless for it's intended purposes. The body doesn't say hey those Amino acids came from Insulin so we'll make them back into Insulin. The body will use them for any of its needs, including making Insulin.

    It may be possible in future to deliver Insulin via the stomach, but only in combination with something that protects its protein from the stomach acids.
    Does that mean we're wasting our time Funny though, that I was told to take it by a surgeon and a physio

    My answer was going to be to make sure you take it with Chronditin...not so sure now!

  2. #12
    Master Mountain Goatess's Avatar
    Join Date
    Mar 2008
    Location
    Whitburn by the sea :-)
    Posts
    2,833

    Re: Glucosamine

    The manufacturer has scientifically researched the effects and benefits of the product! Trials have proven these products have benefit on the joints.
    The absorption of certain oral vitamins etc is accumulative and these products should be taken for at least three months.
    Glucosomine and chondritin are said to have better absorption rates when taken in liquid form.
    Last edited by Mountain Goatess; 18-06-2008 at 06:54 PM.
    Only one who will risk going too far can possibly find out how far one can go. -T.S.Eliot

  3. #13
    Master
    Join Date
    Jan 2007
    Posts
    2,879

    Re: Glucosamine

    Quote Originally Posted by Nila View Post
    Does that mean we're wasting our time Funny though, that I was told to take it by a surgeon and a physio

    My answer was going to be to make sure you take it with Chronditin...not so sure now!
    Nila welcome to the forum! Do you understand the implications of my previous answer?

    Mountain Goatess seems to believes that research has shown that Glucosamine is effective. Yet I've just looked on one of the arthritis web-sites and it states that the research is likely biased.

    I'd go a step further and say that most of the 'research' was never conducted.

    If your surgeon believes in it, why doesn't he offer to inject you with it? The reason he won't is because the pharmaceutical industry hasn't developed it for that purpose. Why not? Probably because they don't see any potential in it.

    The human body unless diseased is quite capable of producing all the chemicals it needs for growth, including Glucosamine.

    Save your money.

  4. #14
    Member
    Join Date
    Jun 2008
    Location
    Up North
    Posts
    35

    Re: Glucosamine

    See now I'm just confused because people are giving different answers, both of which are apparently based on science (although I appreciate scientific research carried out by manufacturers could be biased).

    If the body produces everything it needs then surely we wouldn't need any form of medication to help us heal etc...but we do don't we? That's why mortality rates have dropped with the advancement of medicine. Or am I being thick??

    Never seems to be a simple answer does there! I have recently stopped taking multi-vitamins and minerals because it was suggested to me that I could be taking too much of some vitamins which could be damaging. Now I've got to decide whether to stop taking Glucosamine and Chronditin.

    ....and I thought this forum was here to help

  5. #15
    Master
    Join Date
    Jan 2007
    Posts
    2,879

    Re: Glucosamine

    Quote Originally Posted by Nila View Post
    See now I'm just confused because people are giving different answers, both of which are apparently based on science (although I appreciate scientific research carried out by manufacturers could be biased).

    If the body produces everything it needs then surely we wouldn't need any form of medication to help us heal etc...but we do don't we? That's why mortality rates have dropped with the advancement of medicine. Or am I being thick??

    Never seems to be a simple answer does there! I have recently stopped taking multi-vitamins and minerals because it was suggested to me that I could be taking too much of some vitamins which could be damaging. Now I've got to decide whether to stop taking Glucosamine and Chronditin.

    ....and I thought this forum was here to help
    Nila some people have never needed any medication and still lived a long life. For those who don't recover as well modern medicine has certainly made a difference, but only if the drugs work.

    Some months ago we had a thread on vitamin C, and it was highly entertaining. One person was taking many times the RDA of 60mg, in the belief that it would help him.

    The concept of need is very important in nutrition and implies a limit that cannot be transcended. So if you need 70mg of vitC a day and you take 71mg, that extra 1mg will in no way force your body into utilising it. In fact it puts strain on your organs in having to excrete it.

    Glucosamine though is not a vitamin, and you cannot assume as with a vitamin that it'll be absorbed unchanged.

  6. #16
    Senior Member detritus21's Avatar
    Join Date
    Jan 2007
    Posts
    431

    Re: Glucosamine

    Does Glucosamine work is an interesting question. Looking at a Cochrane Review (a Review of scientific papers) on osteoarthritis and glucosamine gives inconclusive evidence in that some studies show improvement in pain and function and some don't. What it does recommend is that more studies need to be done.

    On a personal note though I believe it to work for me. That is why I take it. It has supposedy has antiinflammatory properties and the ability to help rebuild cartilage. Since I've been taking it my very very mild heal pain has resolved. The thing is if you believe strongly enough that something works then chances are it will do so if someone gave you a dummy pill that looked exactly the same as your glucosamine you may still get the benefits as psychologically its helped.

    I remember in my mispent youth as a sprinter my coach told us that if you exhaled really hard at about 30m you'd run quicker. Next rep all of us blew out as hard as we could as we thought it would make us quicker. Shows you that as humans are generally willing to try anything that will make you improve whether it be make you faster or make your pain less or think that you are reducing your risk of injury. Personally I'm one to take Glucosamine, looking at the evidence for me at present is good enough and looking at a case study of myself I would also justify why I take it.

    Its horses for courses at the end of the day.

  7. #17
    Master Mountain Goatess's Avatar
    Join Date
    Mar 2008
    Location
    Whitburn by the sea :-)
    Posts
    2,833
    Only one who will risk going too far can possibly find out how far one can go. -T.S.Eliot

  8. #18
    Member
    Join Date
    Apr 2007
    Location
    Leeds
    Posts
    19

    Re: Glucosamine

    Two peer-reviewed studies have shown that oral glucosamine supplements do increase the amount of bioavailable glucosamine at the joint.

    This doesn't mean it works, of course.

    But at least it means that the supplement isn't being broken down by the body and used to make hair or toenails.


    Persiani S, Roda E, Rovati LC, Locatelli M, Giacovelli G, Roda A. Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man. Osteoarthritis Cartilage 2005;13:1041-9.

    Persiani S, Rotini R, Trisolino G, Rovati LC, Locatelli M, Paganini D, Antonioli D, Roda A. Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose1 OsteoArthritis and Cartilage (2007) 15, 764-772

  9. #19
    Senior Member No map, no compass's Avatar
    Join Date
    Jul 2007
    Location
    Kendal
    Posts
    460

    Re: Glucosamine

    Quote Originally Posted by Mountain Goatess View Post
    That website is funded by DTC Health Inc., a US company which manufactures glucosamine products, so not exactly an unbiased source of information on the efficacy of glucosamine!

  10. #20
    Master Mountain Goatess's Avatar
    Join Date
    Mar 2008
    Location
    Whitburn by the sea :-)
    Posts
    2,833

    Re: Glucosamine

    Quote Originally Posted by No map, no compass View Post
    That website is funded by DTC Health Inc., a US company which manufactures glucosamine products, so not exactly an unbiased source of information on the efficacy of glucosamine!
    That is true. But it is an example of the type of studies carried out on glucosamine.
    There will always be someone telling us what is good or not good to put into our bodies. Some are there to make money out of us obviously.
    Only our own personal research and beliefs help us to make choices on what is best for us as individuals.
    Only one who will risk going too far can possibly find out how far one can go. -T.S.Eliot

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •