Quote Originally Posted by Oracle View Post
Thanks all.

This makes interesting reading.
A 24 hour track race led to an emergency.

http://www.nbcnews.com/id/37341523/n.../#.XcPkBIqnzmo

Ps they refer acetaminophen , to us is I think paracetamol.
The OD limit is seemingly low.
Acetaminophen is paracetamol. Maximum dose is 1 GM 4 times a day - as the article says, problems may arise when someone takes regular paracetamol at full dose, as well as paracetamol under a different name, or a mixed product which, unknown to them, also contains paracetamol. Liver failure may follow, and often by the time the person feels unwell, it is too late, and a liver transplant is needed.

The article implies that NSAID induced renal problems may be prevented by avoiding dehydration - this of course may result in drinking so much that hyponatremia develops - not nice.

Safer - by far - to avoid both these medications!