Where do I start?
Stitch - it is often caused by food, but could be tiredness / stress. Try changing your breathing patterns - it can get rid. Most runners breath in rhythm with their feet eg. in on a right foot strike and out on the next right foot strike. Try changing to left foot or breath in a rhythm of 3 if you understand and the stitch can be got rid off, particulalry if food / drink induced.
Ibups - I only have experince of ibuprofen and use the normal 200mg strength sainsbury's brand.
My guts are rock solid - always have been - so I don;t tend to suffer whatever I take, but I am careful none the less.
Food 2 hours before running!!
So how do you approach the 3 peaks if you eat 2 hours before start and then you have to run 4 hours +??
You have to train yourself. When I was just a roadie doing 10Ks and under I adopted the 2 hour rule.
Now I can eat and have a coffee 15 minutes vefore a long run without any stitch issues.
Just train yourself to do it.
Cramps - I find that a quick application of ibup gel directly on to the cramping muscle can have an instant effect.
For a twisted ankle though - not so - it takes time to absorb.